Author Topic: Haemophilia is a genetic disorder  (Read 368 times)

0 Members and 1 Guest are viewing this topic.

Offline SCRepublic

  • Jr. Member
  • **
  • Posts: 819
  • Rate this post: +1/-0
Haemophilia is a genetic disorder
« on: November 04, 2008, 11:08:41 PM »
Haemophilia (also spelled as hemophilia, from the Greek haima "blood" and philia "to love"[1]) is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation. In its most common form, Hemophilia A, clotting factor VIII is absent. In Haemophilia B, factor IX is deficient. Hemophilia A occurs in about 1 in 5,000–10,000 male births[2], while Hemophilia B occurs at about 1 in about 20,000–34,000.

The effects of this sex-linked, X chromosome disorder are manifested almost entirely in males, although the gene for the disorder is inherited from the mother. Females have two X chromosomes while males have only one, lacking a 'back up' copy for the defective gene. Females are therefore almost exclusively carriers of the disorder, and may have inherited it from either their mother or father.

These genetic deficiencies may lower blood plasma clotting factor levels of coagulation factors needed for a normal clotting process. When a blood vessel is injured, a temporary scab does form, but the missing coagulation factors prevent fibrin formation which is necessary to maintain the blood clot. Thus a haemophiliac does not bleed more intensely than a normal person, but for a much longer amount of time. In severe haemophiliacs even a minor injury could result in blood loss lasting days, weeks, or not ever healing completely. The critical risk here is with normally small injuries which, due to missing factor VIII, take long times to heal. In areas such as the brain or inside joints this can be fatal or permanently debilitating.

The bleeding with external injury is normal, but incidence of late re-bleeding and internal bleeding is increased, especially into muscles, joints, or bleeding into closed spaces. Major complications include hemarthrosis, hemorrhage, gastrointestinal bleeding, and menorrhagia.

source:wikipedia.com


Living a green body in an ungreen world

GreenBodyTalk.com

Haemophilia is a genetic disorder
« on: November 04, 2008, 11:08:41 PM »
Travel Sale Mountain View

 

Related Topics

  Subject / Started by Replies Last post
0 Replies
474 Views
Last post November 04, 2008, 11:07:03 PM
by SCRepublic
0 Replies
423 Views
Last post November 04, 2008, 11:18:34 PM
by SCRepublic
0 Replies
2 Views
Last post November 09, 2008, 12:13:24 AM
by DrMon
2 Replies
791 Views
Last post November 15, 2010, 12:41:56 PM
by PinoyNurse
0 Replies
1858 Views
Last post June 19, 2010, 09:40:41 AM
by rpmolecule


Posting Disclaimer

The GreenBodyTalk.com Website is not a replacement for professional medical treatment, cure, or diagnosis. When experiencing any health related problem or making changes to existing treatment, it is always suggested to consult medical advices only to qualified health professional. All the posts made to these forums express only the views and opinions made by the respective authors, and do not represent the official opinions of GreenBodyTalk, its administrators, moderators, editorial staff, health contributors, and the GreenBodyTalk Management as a whole. GreenBodyTalk is merely acting as an impartial conduit for constitutionally protected free speech and hence GreenbodyTalk Forum and its principals will accept no liabilities or responsibilities for the statements or posts made.This page was last updated on November 2, 2008. Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 Unported License.

Advertising Disclaimer

We are not related to and do not endorse any product or service being advertised on the site.

Locations of visitors to this page
Google-Translate-Chinese (Simplified) BETA Google-Translate-English to French Google-Translate-English to German Google-Translate-English to Italian Google-Translate-English to Japanese BETA Google-Translate-English to Korean BETA Google-Translate-English to Russian BETA Google-Translate-English to Spanish
Powered by
+ Grab this widget
Some rights reserved. Copyright 2008-2014 Greenbodytalk.com